stypro® Haemostypticum, Medical device
Wound healing with stypro®
stypro®, a biomaterial developed to aid haemostasis, is used in various surgical fields. It is a sterile, highly porous, implantable and resorbable sponge. stypro® possesses an excellent workability. In most cases, the removal of the sponge after haemostasis is not required.
Shapes and cuts
stypro® Cubus: 10 x 10 x 10 mm
stypro® Standard: 50 x 80 x 10 mm
stypro® Special: 50 x 80 x 01 mm
stypro® Tampon: 80 x 30 mm ø
Recent applications have shown stypro® to be beneficial in tissue engineering, i.e. wound healing in soft tissue defects. An expansion of this area can be anticipated for the future.
Product characteristics
stypro® sponges are made from medicinal gelatine (Pharm. Eur.) and retain the capability, inherent to collagen, to initiate blood clotting.
stypro® works physiologically without thrombin or other additives.
Resorption occurs within approx. three weeks after implantation. stypro® may be saturated with physiological saline solution without losing its haemostatic properties.
stypro® sponges saturated with blood will not stick to instruments.
All stypro® cuts possess an interconnecting porosity. At present, there are four types of cuts of which Cubus is the one used most often in the dental field, whereas Standard or Special are applied in more extensive surgical procedures.
stypro® is a safe product. Scientific research has found no evidence of PERV-DNA-sequences (PERV = porcine endogenous retrovirus).
Packaging is safe and double sterile. After manufacture, the material is gamma-sterilized.
The Cubus is packed single-sterile in a practical two-piece blister.
Indications in dentistry and maxillofacial surgery
Haemostasis and filling of alveolae after tooth extractions. Filling of soft tissue defects in surgical procedures. Findings in orofacial cleft surgery are documented as well (Pape 2003).
Indications in oral surgery
Doumat et al. (2005) verified in 125 patients stypro's excellent suitability for various complex procedures in oral surgery.
Indications in implantology
Broos (2004) demonstrated in several cases how stypro® can be used as a non-woven membrane (Special / Cubus) in sinus floor elevations to protect the Schneiderian membrane.
The stypro® Tampon is used in haemorrhoidal surgery. Minor secondary bleeding after surgical procedures can, for the most part, be avoided – a particular advantage in ambulatory surgery.
In general, the removal of the tampon is not required in a clinical application, since it is excreted naturally once the healing process begins.