Curavisc® (hyaluronic acid)

Osteoarthritis Treatment with Curavisc®

In an osteoarthritis, there is a qualitative and quantitative deficiency of natural hyaluronic acid in the affected joint (e.g., the knee joint), which normally provides the necessary lubrication of the joint. In these cases the physician can use Curavisc®, a hyaluronic acid produced by a fermentation process, to supplement the synovial fluid. This process is called viscosupplementation, that is, the supplementation of synovial fluid.

Using a syringe, the active substance is injected directly into the joint space (intra–articular injection).

This makes it possible — with correct diagnosis and correctly applied therapy —, to attain increased mobility and pain relief in the earlier stages of the osteoarthritis. This can contribute to an enhanced quality of life for the patient. Patients are frequently free of pain for an extended period (up to 12 months) or they require markedly less pain medication. Adverse effects on Gastrointestinal and cardiovascular system are not known.

A Curavisc® course of treatment is generally comprised of five injections which are administered at one week intervals.

Commercial Presentations:

1 pre–filled syringe 20mg/2 mL – PZN: 1442295

Authorization in the European Economic Area (CE 0483)

Curavisc® is to be administered only by a physician.
Pursuant to the regulations currently in force Curavisc® is normally not reimbursed by statutory health insurance plans.

Product Benefits:

  • Viscoelastic solution: Improved lubrication in virtue of an average molecular weight of approximately 1,200,000 – 1,400,000 Daltons
  • No allergenic potential against chicken protein in virtue of high–purity hyaluronic acid produced by a fermentation process
  • Pre–filled syringes containing 2 mL of sterile solution and Luer–lock connection, and documentation stickers.
  • Improved syringe guide using good fingertip guidance


“Viscosupplementation”, i.e., supplementation of the synovial fluid in arthrosis patients

Indications may differ from country to country